Apoptosis in the colonic crypt, colorectal adenomata, and manipulation by chemoprevention.

نویسندگان

  • Nicholas J West
  • Edward D J Courtney
  • Andrew P Poullis
  • Roger J Leicester
چکیده

This review discusses the biology and the methods of assessment of apoptosis, of which, the monoclonal antibody M30 would seem to be the most useful; the role of apoptosis in the etiology of colorectal cancer; and its use as a marker to monitor the beneficial effects of chemopreventative interventions to reduce the development of colorectal cancer within the context of clinical trials.

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عنوان ژورنال:
  • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

دوره 18 6  شماره 

صفحات  -

تاریخ انتشار 2009